ABOUT GENETIC METHYLATION TEST GARY BREAKA

within the human genome, 5mC is routinely located in CpG dinucleotides, with these web sites remaining hotspots for mutations including in tumor suppressor genes. For example, CpG island (CGI) mutations within the coding region of p53, a gene involved with genome stabilization and cell cycle/apoptotic responses, add to ~25% of its inactivating muta